Stress and Brain Atrophy
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چکیده
منابع مشابه
Stress and brain atrophy.
Studies in animals showed that stress is associated with changes in hippocampal function and structure, an effect mediated through decreased neurogenesis, increased glucocorticoids, and/or decreased brain derived neurotrophic factor. Antidepressants and some anticonvulsants block the effects of stress and/or promote neurogenesis in animal studies. Patients with posttraumatic stress disorder (PT...
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Alcoholism has no satisfactory definition, yet no more useful term is available to describe chronic and deleterious over-consumption. Alcohol is mostly drunk for its pharmacological effects on the nervous system, so not surprisingly the brain is one of the organs that suffers most-along with the liver, which detoxifies the alcohol. The effects on the nervous system include direct intoxication, ...
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Neuroimaging in Alzheimer’s disease (AD) has moved beyond the stage where it was used purely to exclude other disease processes. Structural brain magnetic resonance imaging (MRI) is useful to assess hippocampal atrophy on coronal slices; clinicians can use a simple visual rating scale, which can help to confirm the diagnosis of AD. Another useful indication for neuroimaging is to assess the con...
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ژورنال
عنوان ژورنال: CNS & Neurological Disorders - Drug Targets
سال: 2006
ISSN: 1871-5273
DOI: 10.2174/187152706778559309